105 CMR 910.200 - Compliance with Standards
(A) Each
research institution shall comply in all respects with the standards set forth
in
105 CMR 910.000 for the
humane handling, care, treatment, and transportation of dogs and cats;
provided, that research involving the use of dogs or cats that, due to
experimental design, does not conform to regulations or standards promulgated
by the Commissioner must be approved, prior to the conduct thereof, by the
institutional animal research committee and/or the attending veterinarian of
the licensee. The approval must be in writing and must be placed on file at the
institution, subject to inspection by the Commissioner or his designee. In
granting approval to research projects which do not conform to these standards,
the animal care committee and/or the attending veterinarian shall abide by the
"Guidelines for the Care and Use of Laboratory Animals" published by the
National Institutes of Health as follows:
(1)
The research must be such as to yield fruitful results for the good of society
and not random or unnecessary in nature.
(2) The experiment must be based on knowledge
of the disease or problem under study and so designed that the anticipated
results will justify its performance.
(3) Statistical analysis, mathematical
models, or in vitro biological systems must be used when appropriate to
replace, reduce or complement animal experiments and to reduce numbers of
animals used.
(4) The experiment
must be conducted so as to avoid all unnecessary suffering and injury to the
animal.
(5) The scientist in charge
of the experiment must terminate it whenever he/she believes that its
continuation may result in unnecessary injury or suffering to the
animals.
(6) Care of animals must
be such as to minimize discomfort and the consequences of any disability
resulting from the experimentation, in accordance with acceptable practices in
veterinary medicine.
(B)
In addition to the specific requirements of
105 CMR 910.000 for the
care, treatment, and handling of dogs and cats, each licensee shall treat all
other research animals in a manner consistent with the intent of
105 CMR 910.000.
Notes
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