25 Pa. Code § 250.605 - Sources of toxicity information
(a) For site-specific standards, the person
shall use appropriate reference doses, reference concentrations, cancer slope
factors and unit risk factors identified in Subchapter C (relating to Statewide
health standards), unless the person can demonstrate that published data,
available from one of the following sources, provides more current reference
doses, reference concentrations, cancer slope factors or unit risk factors:
(1) Integrated Risk Information System
(IRIS).
(2) United States
Environmental Protection Agency, National Center for Environmental Assessment
(NCEA) Provisional Peer-Reviewed Toxicity Values (PPRTV).
(3) Other sources:
(i) Health Effects Assessment Summary Tables
(HEAST).
(ii) Agency for Toxic
Substances and Disease Registry (ATSDR) Toxicological Profiles.
(iii) California EPA, California Cancer
Potency Factors and Chronic Reference Exposure Levels.
(iv) EPA criteria documents, including
drinking water criteria documents, drinking water health advisory summaries,
ambient water quality criteria documents and air quality criteria
documents.
(v) EPA Human Health
Benchmarks for Pesticides (HHBP).
(vi) EPA PPRTV Appendix.
(b) If no toxicity values are
available from sources identified in subsection (a), the person may use the
background standard or meet one of the following:
(1) Develop for the Department's review in
the risk assessment report one of the following:
(i) Chemical-specific toxicity values in
accordance with the methods in the most current EPA guidelines or protocols,
approved by the Department, using corroborated peer-reviewed data published in
a scientific journal, if they exist.
(ii) Toxicity values developed from
appropriately justified surrogates.
(2) Use the minimum threshold medium-specific
concentration, as the site-specific standard, with an assumed risk of 1 x
10-5 for purposes of calculating cumulative risk for
the regulated substances identified in Appendix A, Table 6.
Notes
The provisions of this § 250.605 amended under sections 104(a) and 303(a) of the Land Recycling and Environmental Remediation Standards Act (35 P.S. §§ 6026.104(a) and 6026.303(a)); and section 1920-A of The Administrative Code of 1929 (71 P.S. § 510-20).
State regulations are updated quarterly; we currently have two versions available. Below is a comparison between our most recent version and the prior quarterly release. More comparison features will be added as we have more versions to compare.
No prior version found.